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Homemade Guajillo Chile Sauce (Instant Pot and Traditional Methods)

By Brianna Simmons ยท Published: May 7, 2021 ยท Updated: September 26, 2025

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Every good cook needs an arsenal of secret ingredients, just a little something that makes other dishes better.  For me one of those secret ingredients is homemade guajillo chile sauce.  Smokey, earthy and a little tangy I always have a batch of  this guajillo sauce on hand to give an extra depth of flavor to any Mexican or Southwestern dish. Whether you make it with the traditional soaking method or using the Instant Pot this guajillo chile sauce will soon be a favorite.

Guajillo Chile Sauce

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What are guajillo chiles?

Guajillo Chile Sauce

Guajillo chiles are the dried form of the mirasol pepper and is one of the most popular dried chiles in Mexico. Guajillo chiles are about 3-5 inches long, dark red in color with a leathery skin and should be soft and pliable. Guajillo chiles have a mild spice level (2,500-5,000 Scoville Heat Units) and a deep smoky flavor. They are traditionally toasted and ground into guajillo chile powder or rehydrated to be used in sauces.

How to use guajillo chile sauce

Guajillo Chile Sauce

I use this guajillo sauce in a number of Mexican and southwestern dishes including chili, charro beans, black beans and as part of a marinade for pork tacos. Guajillo sauce is also great with enchiladas, mole sauces and salsas. This sauce is great anywhere you’d like to add an extra depth of smokiness (like this smoked pork loin or smoked tri tip), the possibilities are endless!

What can I use instead of guajillo chiles?

If you can’t find guajillo chiles (they are available in major grocery stores, Latin markets or you can also find guajillo chiles online) you can substitute ancho chiles, pasilla negro chiles or cascabel chiles for a similar flavor profile.

How to Make Guajillo Chile Sauce

Guajillo chile sauce - guajillo chiles
Guajillo chile sauce - ingredients in pot

To make guajillo chile sauce you can prepare it with the traditional soaking method but I prefer using my Instant Pot as I feel the pressure cooker extracts a bit more flavor from the guajillos. For both methods you’ll combine guajillo chiles (stems and seeds removed), water, cumin, dried oregano, garlic, salt and sugar. For the traditional soaking method first heat the water on the stove or with an electric kettle and then cover and soak the chile and spice mixture for 30 minutes or until the chiles are softened. For the Instant Pot add all of the ingredients and pressure cook for 8 minutes, then let natural release for at least 5 minutes then quick release if needed. To finish the sauce transfer everything along with 2 tablespoons of apple cider vinegar to a larger capacity blender (I adore my Vitamix and use it daily) and blend until smooth. Store your guajillo chile sauce in the refrigerator for 1 week or in the freezer for up to a month.

Guajillo chile sauce

If you like this guajillo chile sauce be sure to take a look at some of my other recipes!

Homemade Hot Honey Recipe

Easy Brine for Chicken Wings

Oven Baked BBQ Chicken Wings

Easy Pimento Cheese

Roasted Poblano Salsa

Coffee BBQ Sauce

Guajillo Chile Sauce Pinterest Image

If you make this Guajillo Chile Sauce please be sure to leave a comment and/or give this recipe a rating! Be sure to follow me on Facebook and Pinterest for my latest recipes. Also, if you do make this recipe please tag me on Instagram, Iโ€™d love to see what you guys are making!

Guajillo Chile Sauce

Guajillo Chile Sauce (Traditional and Instant Pot Methods)

This Guajillo Chile Sauce is a great way to add smoky flavor to your favorite Mexican and southwestern recipes. Discover this easy recipe (with an option to use the Instant Pot) for guajillo sauce to add flavor to tacos, enchiladas, beans, chili, salsas and more.
4.82 from 91 votes
Print Recipe Pin Recipe
Prep Time 5 minutes mins
Cook Time 30 minutes mins
Total Time 35 minutes mins
Course Condiments, Sauces
Cuisine American, Mexican, Southwestern
Servings 2 cups

Equipment

  • Instant Pot
  • Blender

Ingredients
  

  • 1.5 cups water
  • 2 oz guajillo chiles, stems and seeds removed 5 large or 10 small
  • 2 cloves garlic
  • 2 tsp kosher salt
  • 1.5 tsp sugar
  • 1/2 tsp ground cumin
  • 1/2 tsp Mexican oregano
  • 2 tbsp apple cider vinegar

Instructions
 

Traditional soaking method

  • Boil water on the stove or using an electric kettle. Add water, chiles, garlic, salt, sugar, oregano and cumin to a large bowl and cover. Soak for 30 minutes or until chiles are soft.

Instant Pot Method

  • Add water, chiles, garlic, salt, sugar, oregano and cumin to the Instant Pot. Pressure cook for 8 minutes, let natural release for at least 5 minutes and then quick release if needed.

To finish the guajillo chile sauce

  • Transfer the sauce to a blender along with apple cider vinegar. Blend until smooth.

Notes

Guajillo chile sauce can be stored in the refrigerator for 1 week or in the freezer for up to a month.
Keyword chile pepper, condiment, instant pot, sauce

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4.82 from 91 votes (47 ratings without comment)

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Comments

  1. Julie says

    May 8, 2021 at 4:11 pm

    I can almost smell this sauce! So flavorfulย 

    Reply
  2. Biana says

    May 8, 2021 at 4:43 pm

    5 stars
    Such a great looking sauce! Will be a perfect marinade to make some taco meat in the Instant Pot.

    Reply
  3. Tara says

    May 8, 2021 at 8:27 pm

    5 stars
    Oh yum! This guajillo chile sauce sounds absolutely amazing! I love how you included the instructions for both the traditional soaking method and for the instant pot.

    Reply
  4. Irina says

    May 8, 2021 at 9:18 pm

    5 stars
    I have never made chile sauce myself, but it seems my chance to give it a try! Your recipe sounds delicious and easy to make too. ๐Ÿ™‚

    Reply
    • Billie Mills says

      January 9, 2022 at 9:01 pm

      5 stars
      You simply must use dried chili pods. There are so many great ones, Anchos, Pasillas, Guajillos, Cascabels, Pequins…the list is huge. Each has its own special flavor. Making chili sauce from pods is easy beans! Good luck!

      Reply
  5. Colleen says

    May 8, 2021 at 10:58 pm

    5 stars
    Enchiladas are on our menu this week, and I’m going to make a batch of this sauce for them. It looks so flavorful and delicious!

    Reply
  6. Allyssa says

    May 13, 2021 at 9:53 am

    5 stars
    Thank you so much for sharing this really tasty chile sauce! It’s so easy to make and taste delicious! It’s our new favorite and I will really make one again!

    Reply
  7. Amy says

    May 28, 2021 at 11:44 pm

    5 stars
    Such a great recipe! Tried it in the instant pot and turned out perfectly!

    Reply
  8. Oscar says

    May 29, 2021 at 12:00 am

    5 stars
    Great recipe. Loved this sauce.

    Reply
  9. Alexandra says

    May 29, 2021 at 12:29 am

    5 stars
    This sauce is delicious with so many things!

    Reply
  10. michele h peterson says

    May 29, 2021 at 2:47 am

    5 stars
    Love this guajillo sauce on shredded chicken tacos!

    Reply
  11. Lilly says

    May 29, 2021 at 7:59 pm

    5 stars
    I tried the instant pot method and it worked perfect! Thanks for sharing!

    Reply
  12. Elizabeth Flight says

    May 30, 2021 at 1:31 am

    5 stars
    Great recipe! Will definitely make again!

    Reply
  13. Brianna May says

    June 1, 2021 at 3:10 pm

    5 stars
    Yum!!

    Reply
  14. Debra says

    June 1, 2021 at 11:38 pm

    5 stars
    So easy and so flavorful!

    Reply
  15. Allyssa says

    June 10, 2021 at 12:09 pm

    5 stars
    Very helpful! It taste amazing and very flavorful! Thank you so much for sharing this homemade guajillo chili sauce! Fam really loves it!

    Reply
  16. Liz says

    June 10, 2021 at 5:56 pm

    5 stars
    I’ve been having so much fun with sauces lately- this one is a new favorite! Thanks for the recipe!

    Reply
  17. Jere Cassidy says

    June 10, 2021 at 8:08 pm

    5 stars
    I love making homemade sauces and we eat Mexican cuisines all the time so this is a perfect recipe to make and keep on hand.

    Reply
  18. Preston says

    June 13, 2021 at 6:35 pm

    You didn’t mention removing the seeds, but I am pretty sure one is supposed to.

    Reply
    • Brianna says

      June 14, 2021 at 12:44 am

      I mentioned it in the body of the blog post but you’re right, I didn’t put it in the recipe. Thanks for pointing it out, all fixed ๐Ÿ™‚

      Reply
  19. Linda says

    June 24, 2021 at 5:08 am

    5 stars
    So excited for this chile sauce. It’s flavorful and perfect for tacos

    Reply
  20. Liz says

    June 24, 2021 at 12:29 pm

    5 stars
    I had no idea it was possible to make guajillo chile sauce at home! This is such a great way to amplify my dinner. My husband loves it, too!

    Reply
  21. Heather says

    June 24, 2021 at 7:16 pm

    I’ve always seen these dried peppers at the store but had no idea what to do with them! I love how easy this recipe sounds – YAY for anything that can be made in the IP ๐Ÿ™‚ Cannot wait to finally buy those guajillos and give this a try.

    Reply
  22. veenaazmanov says

    June 25, 2021 at 1:45 am

    5 stars
    Sounds like a great option to stock this sauce so flavorful in my kitchen. I would love to try amazing recipes and treat my family and friends. Thanks.

    Reply
  23. Ksenia says

    June 27, 2021 at 10:09 am

    5 stars
    We eat A LOT of Mexican food in my house, and I love experimenting with different dried chillies. Canโ€™t wait to put this paste to use!

    Reply
  24. Erin says

    June 27, 2021 at 1:54 pm

    Thanks for including an IP option! I’m doing all the cooking out on the balcony these days (so hot!) so I will be sure to use that method. Can’t wait!

    Reply
  25. Alex says

    June 27, 2021 at 2:22 pm

    I so wish we had those peppers here in Germany! I bet this sauce would be tasty on so many things. And I love that you can freeze it!

    Reply
  26. Jenny says

    June 27, 2021 at 7:10 pm

    5 stars
    Thanks so much for sharing this. I am always looking for great sauces and toppings, and your guajillo chile is amazing. Hubby went bananas over it. I am sure we will be making it frequently.

    Reply
  27. Adriana says

    June 28, 2021 at 5:05 am

    5 stars
    I am Mexican and homemade guajillo sauce is a must have. Super versatile as can be used beyond enchiladas.

    Reply
  28. Natalie says

    June 28, 2021 at 11:24 am

    5 stars
    That sauce sounds so good. I think I never tried anything like it before. But now I definitely must make this. The texture is amazing. And I love added cumin. I’m making this for sure.

    Reply
  29. Amanda Scarlati says

    July 26, 2021 at 11:51 pm

    5 stars
    I love making things from scratch and this recipe is so full of flavor!

    Reply
  30. Alexandra says

    July 26, 2021 at 11:52 pm

    5 stars
    So many delicious ways to use this sauce!

    Reply
  31. Alexa says

    July 26, 2021 at 11:56 pm

    5 stars
    Loved it with our homemade tacos!!

    Reply
  32. Elizabeth Flight says

    July 27, 2021 at 12:08 am

    5 stars
    Such a great recipe! So delicious!

    Reply
  33. Debra says

    July 27, 2021 at 12:42 am

    5 stars
    Yum. Will be making a double batch next time. We loved it.

    Reply
  34. Melinda says

    July 27, 2021 at 1:12 am

    5 stars
    This recipe will be perfect with my favorite enchiladas, thanks for sharing!

    Reply
  35. Addie says

    July 27, 2021 at 2:44 am

    5 stars
    So spicy and flavorful!

    Reply
  36. Brianna May says

    July 27, 2021 at 2:00 pm

    5 stars
    Yum!

    Reply
  37. Jamie says

    July 28, 2021 at 1:00 am

    5 stars
    This was great on tacos! Loved it!

    Reply
  38. Kayla DiMaggio says

    August 9, 2021 at 11:15 pm

    5 stars
    Wow! This chili sauce was amazing! I loved the flavor that it imparted!

    Reply
  39. Amy says

    August 9, 2021 at 11:32 pm

    5 stars
    This sauce was awesome and the instant pot method is so easy!

    Reply
  40. Jean says

    August 9, 2021 at 11:36 pm

    5 stars
    this is a genius recipe and way better than store bought!

    Reply
  41. Anaiah says

    August 9, 2021 at 11:45 pm

    5 stars
    This guajillo chile sauce came out perfect! I used the instant pot method and it could not be more easy. We’re having this with enchiladas and beans for our dinner. Thank you for this!

    Reply
  42. Raquel says

    August 10, 2021 at 1:42 am

    5 stars
    So great with enchiladas!

    Reply
  43. Addie says

    August 10, 2021 at 1:53 am

    5 stars
    Love the instant pot method! So easy!

    Reply
  44. michele says

    August 10, 2021 at 5:22 pm

    5 stars
    Thanks for this! It’s a tasty chile salsa that works well with so many dishes!

    Reply
  45. Myra says

    October 7, 2021 at 3:23 am

    This sauce is so good I can eat it like soup. I ordered a huge bag of guajillo peppers by mistake. I never used them before. Recipe was so easy. I put them on drumsticks and baked for 30mins at 400 degrees uncovered. Then I put more sauce on and covered with foil. Baked another 30mins at 310 degrees. Came out delicious. Can’t wait to try with other meat dish. Maybe tomorrow.๐Ÿ˜‹

    Reply
    • Brianna says

      October 8, 2021 at 12:20 am

      5 stars
      Myra, I’m thrilled you like it! Putting it on drumsticks is a fantastic idea ๐Ÿ™‚

      Reply
  46. Dave Cearley says

    January 27, 2022 at 5:37 am

    5 stars
    The place I first discovered this sauce serves it warm. I routinely have it with their Mexicana Eggs. Love the stuff, took me a while to identify what chilis were used.
    Thanks for the recipe.

    Reply
  47. Jason says

    October 5, 2022 at 6:31 pm

    3 stars
    Way way too salty! I’d recommend cutting 1/2 the salt. It makes about 2 cups so 2 tsps per cup is too much imo… Otherwise it’s an easy recipe.

    Reply
  48. Liz says

    November 27, 2023 at 10:27 pm

    5 stars
    Thank you for this! I bought a huge bag of these peppers on a whim. Had no idea what to do with them after I got home. I made your sauce & used it with some homemade chili – FANTASTIC! Thank you so much for taking the time to write this up and share it! I used the recipe exactly as you wrote it, but only 1/2 quantity. It exactly fills a small jar! Thank you!

    Reply
    • Brianna Simmons says

      November 28, 2023 at 1:23 am

      I’m so glad you liked it! It really is one of those sauces that adds that extra something to whatever you add it to.

      Reply
  49. Daniel Gomez says

    October 29, 2025 at 7:10 pm

    Used Guajillo peppers!! Smokey, sweet and delicious!

    Reply
    • Brianna Simmons says

      October 31, 2025 at 12:08 am

      Daniel, that’s great to hear! How will you be using you guajillo sauce?

      Reply

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